Using Bovine Serum Albumin (BSA) as a model protein for aggregation and degradation, a = 2 mg/mL sample was prepared in 50 mM phosphate. Monitoring Biopolymer (Protein) Degradation Finally, three samples of PS-A were dissolved in toluene (Tol), butyl acetate (BAc), or THF and allowed to degrade at 55☌ with a stirring rate of 100 RPM for 10 hours. A subsequent experiment was performed with stirring (mechanical stress) at 100 RPM and thermally stressed from 30☌ – 55☌ for the entirety of the experiment. These samples were then thermally stressed at a temperature range from 30☌ – 55☌ for 15 hours to monitor degradation. Samples of polystyrene (PS-A) were dissolved in THF at a = 10 mg/ml, placed into cuvettes, and loaded into ARGEN™ sample cells. Two Polystyrene (PS) standards, 16,500 g/mol and 185,000 g/mol, and an uncharacterized PS sample (PS-A) were serially diluted with tetrahydrofuran (THF) from 15.0 mg/mL to 0.166 mg/mL, generating an 8-point Debye plot for extrapolation of absolute molecular weight of each sample using the Debye equation: The ARGEN™ control software features an intuitive interface for all aspects of experimental design and independent control of each cell for parallel parameter adjustment and real-time data processing. This allows for a highly flexible approach to experimental design. The device is equipped with 16 independently controlled sample cells, permitting the user to establish thermal, chemical, and mechanical (stirring) stress parameters on each sample concurrently. These features enable teams to develop biologic formulations up to 16-fold faster.ĪRGEN™ utilizes fixed angle (90°), simultaneous multiple sample light scattering (SMSLS) technology which provides rapid, real-time, continuous data collection for characterizing qualitative and quantitative properties of target molecules. The instrument uses a multi-stressor testing platform powered by static light scattering detection and intuitive data processing. Learn More Argen LMT Lab Day Education SeriesĪll lectures will be held at the Argen Lecture Room, Grand CD North, Ballroom Level, East Tower.ARGEN™: Smart & Rapid Therapeutic Biopolymer DevelopmentĪRGEN™ is a high throughput tool for the rapid assessment of the stability and viability of therapeutic proteins, peptides, and biopolymers. With our ArgenIS Angled Screw Channel Abutments, you can achieve unparalleled esthetics with the freedom to place the access hole anywhere between 0 ° and 25° in a 360° radius.Īrgen is also expanding our ArgenIS Implant Systems offering with new engaging and non-engaging Ti bases in multiple collar heights and a new multi-unit system including straight and angled abutments, Ti bases, parts, and tools. Laboratories, doctors, and patients can have complete peace of mind knowing the performance of Argen’s implant parts is assured and covered by an extensive warranty. Our custom abutments and screws are certified OEM-equivalent they function comparably to OEM (Original Equipment Manufacturer) parts. Trade ShowsĪrgenIS Custom Abutments are 5-axis precision-milled, FDA 510(k) cleared, and fully integrated for intraoral scanning with digital implant models. Thank you to all who have attended in the past and we hope to see you in 2023. ![]() And, we have a stellar lineup of presentations about the business and workflow benefits of multilayer zirconia, why switch to digital dentures, design tips from our expert trainer, and the clear aligner market and opportunity.Īrgen will not be hosting our Customer Appreciation Bash in 2022. ![]() Back by popular demand is our Good Morning Argen Panel with a new group of esteemed panelists. Hot Chicago News New products, amazing education series - we look forward to seeing you all back in Chicago!Ĭome see Argen’s best-selling multilayer zirconias: ArgenZ HT+Multilayer & ST Multilayer, talk to our team about how to get started with Argen Clear Aligners, find out more about our expanded ArgenIS line including new and non-engaging Ti bases in multiple collar heights and straight and angled multi-unit abutments, and take advantage of our best-price-of-the-year equipment deals.Įarn CE credit at Argen's education series.
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